MyoAAV for Targeted Skeletal Muscle Delivery for DMD & XLMTM
Time: 1:00 pm
day: Post-Conference Day
Details:
- A family of muscle-tropic capsids identified by directed evolution in mice and primates
- MyoAAV transduction is dependent on integrin heterodimers in mouse and human cells
- MyoAAV administration at low dose results in therapeutic efficacy in disease models
- Systemically-administered MyoAAV transduces primate muscles highly efficiently
