Ivana Petrovic Koshmak

Ivana Petrovic Koshmak

Company: BIA Separations

Job title: Head of Upstream Process Development


Analytical Tools to Improve Empty/Full Ratio in Initial Stages of AAV Process Development 11:30 am

Empty AAV capsids are known contributors of immunogenicity in gene therapy products Reducing them below 10% during downstream process is difficult if empty capsids constitute vast majority of total AAV produced in harvest. The solution is further optimization of harvest production Determining the factors that improve empty/full ratio is possible already at the initial stages…Read more

day: Day One

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