Mike Stec

Mike Stec

Company: Regeneron

Job title: Staff Scientist


Antibody-Mediated Retargeting of AAV9 to Skeletal Muscle for Safe & Effective Treatment of Muscle Diseases 10:00 am

Poor distribution of AAV to skeletal muscle and uptake in off-target tissues limits the efficacy and safety of gene therapy for muscle diseases Using REGN’s antibody-based AAV retargeting platform, we demonstrate enhanced delivery of therapeutic transgenes to skeletal muscle in mouse models of muscle disease, while simultaneously limiting transduction of off-target tissues (e.g., liver) Improved…Read more

day: Day Two

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