Ratish Krishnan

Company: Millipore Sigma

Job title: Associate Director, Novel Modalities

Bio:

Ratish Krishnan is a Senior Strategy Consultant in the Novel Modalities BioProcessing group for the Americas. He is passionate about providing solutions to bring treatments to market. A Process Development Scientist by background, he has over 13 years of experience in vaccine, monoclonal antibodies and viral vector modalities from pre-clinical to late stage process characterization, validation and commercialization activities such as BLA authoring. As a Biochemical engineer, he holds a Master’s degree in biotechnology from the Pennsylvania State University. Ratish has managed process development teams at Novartis and Pfizer prior to his current role where he serves as global subject matter expert for viral vector manufacturing and provides strategic guidance to internal stakeholders and key customers. He is active in his thought leadership activities at scientific conferences, technical webinars, and key authorship contributions in peer-reviewed articles and white papers.

Seminars:

Guidance for AAV Process Development Based on Cost Modeling 3:45 pm

Production of adeno-associated virus (AAV) and other viral vectors used for gene therapy faces challenges due to high manufacturing costs and compressed process development timelines compared to traditional biopharmaceuticals Many process development activities may be undertaken to reduce manufacturing costs, but these costs are often not directly related to the process improvements being considered In…Read more

day: Day One

Panel Discussion: Overcoming Manufacturing Challenges with Advancing Programs 4:15 pm

Discussing the additional potency assays requested by regulators Debating the affect of quality on efficacy Approaching later programs and ensuring quality scale up and avoiding bottlenecks with large doses required for high muscle massRead more

day: Day One